Two genetic deletions in human genome linked to aggressive prostate cancer...
An international research team led by Weill Cornell Medical College investigators have discovered two inherited-genetic deletions in the human genome linked to development of aggressive prostate...
View ArticleBreakthrough study finds 'master switches' in colon cancer
A team of researchers at Case Western Reserve University School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on segments of DNA located between genes, or...
View Article'Junk DNA' can sense viral infection
Once considered unimportant "junk DNA," scientists have learned that non-coding RNA (ncRNA) RNA molecules that do not translate into proteins play a crucial role in cellular function. Mutations in...
View ArticleChromatin marks the spot in search for disease pathways
In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of...
View ArticleLong noncoding RNAs control development of fat cells
Whitehead Institute researchers have identified a previously unrecognized layer of genetic regulation that is necessary for the generation of undesirable white fat cells. When this regulation is...
View ArticleNot dead yet: Junk DNA is back
A controversy at last: most of our DNA is junk, no it isn't, yes it is. Actually, I think it is – up to 90% really is junk.
View ArticleScience of genome-sequencing marks 10 years
A decade after completion of the Human Genome Project on April 14, 2003, a top official of the National Institutes of Health surveyed the rarefied view from that mountaintop:
View ArticleBrain development is guided by 'junk' DNA that isn't really junk
(Medical Xpress)—Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have...
View Article'Junk DNA' plays active role in cancer progression, researchers find
Scientists at The University of Nottingham have found that a genetic rogue element produced by sequences until recently considered 'junk DNA' could promote cancer progression.
View ArticleKey protein accelerates diabetes in two ways
The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham (UAB) study published online...
View ArticleNon-coding DNA implicated in type 2 diabetes
Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study.
View ArticleNew genetic test may change how brain cancer is treated, researchers say
(Medical Xpress)—Scientists at Virginia Tech's Virginia Bioinformatics Institute working with the Center for Cancer and Blood Disorders at Children's National Medical Center have found a new way to...
View ArticleResearchers find ovarian cancer oncogene in 'junk DNA'
Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease.
View ArticleMicroRNA, the puppet master of the genome
We all know how irritating it is to have an inbox flooded with junk mail. Fortunately email providers these days contain filters to keep the junk mail at bay. As a result the junk mail folder tends to...
View ArticleJuvenile arthritis: why genetic risk is not in the genes
Scientists have been finding that genetic risk for many diseases lies primarily in noncoding parts of the genome, which used to be called "junk DNA," and not in the genes themselves. But that finding...
View Article'Junk' DNA plays role in preventing breast cancer
Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.
View ArticleScientists find surprising impact of junk DNA and RNA in cancer
"Human satellite II," an exceptionally high-copy but unexplored sequence of the human genome thought of as "junk DNA," has a surprising ability to impact master regulators of our genome, and it goes...
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